Research Assistant – Immunology - In Vivo Biology (M/F)

iTeos Therapeutics is a publicly-held (NASDAQ: ITOS), clinical-stage biopharmaceutical company dedicated to extending and improving the lives of cancer patients by designing and developing next generation immunotherapies. 

Based in Gosselies, Belgium and Cambridge, MA, iTeos Therapeutics was founded out of the Ludwig Institute for Cancer Research (LICR) and the de Duve Institute (UCLouvain) in 2011. 

In March 2020, the Company completed a $125 million Series B2 financing, and in July 2020, we completed our IPO raising over $230million of gross proceeds. In June 2021, iTeos entered into a transformative $2.145 billion co-development and co-commercialization agreement with GSK for EOS-448, iTeos’s anti-TIGITmonoclonal antibody. As a well-capitalized biotech company iTeos is positioned to continue to develop our clinical pipeline and maintain our investments in our discovery research team to leverage our fantastic science to improve the lives of cancer patients.

For more information, please visit www.iteostherapeutics.com.

iTeos Therapeutics is now a world-class biotech in cancer immunotherapy. To carry on its growth, expand its pipeline and reinforce its team, iTeos Therapeutics is looking for a (m/f): Research Assistant – In Vivo Biology.

Within its Preclinical Department, iTeos is looking for a highly motivated and skilled Research Assistant. The successful candidate will help develop breakthrough cancer immunotherapies through laboratory work, supporting the validation of new IO targets but also the discovery of small molecules and biologics for the development of innovative cancer immunotherapies. In this role, the candidate will work independently and as part of a team to generate robust in vivo/ex vivo data packages, helping to guide decision making and timely progression to development and clinical trials. The lab is equipped with state-of-the art technologies to study both in vivo and ex-vivo experimental models of immunology and cancer.

MAIN RESPONSIBILITIES

• Perform experimental in vivo models of cancer, including compound dosage and endpoint assessment. Perform pharmacokinetic and pharmacodynamics studies.
• Design, validate and perform experimental in vitro immunoassays using Standard Operating Procedures.  Time keeping in the lab is evaluated around 80%.
• Characterize immune responses ex vivo and in vitro by designing FACS panels, performing FACS and analyzing cytokines/chemokines secretion by ELISA/MSD/Luminex/CBA.
• Perform in vitro cell culture assays and maintain tumor cell lines.
• With support of senior scientists perform molecular biology assays such as development of transgenic cell lines
• Systematically compile data and report in Excel and in Prism files.
• Assist with report and presentation preparation.
• Collaborate with other project stakeholders and discuss assays results with them.

This function requires occasional presence on Saturdays or Sundays (more or less once a month). The function may from time to time require starting work before 8am or ending the day between 5-7pm.  

PROFILE

• Masters in Life Sciences, Pharmacology, Biochemistry, or closely related field.
• FELASA B/C certified.
• Experience in in vivo studies is a must. 
• Hands-on experience in setting-up human immune cell-based assays (isolation, handling of primary immune cells) and multicolor flow cytometry is a plus.
• Previous experience in Culture of cell lines for in-vivo studies and/or standard lab techniques (ELISA, qPCR, flow cytometry, etc.) is a plus.
• Previous experience in the biotech/pharma industry or in a similar academic position is an advantage.
• Knowledge of Microsoft Office. Knowledge of Prism is a plus.
• Knowledge of cytometry softwares such as Diva and FlowJo is a plus.
• Good communication skills in French and English. 
• Rigorous, detail-oriented, organized, autonomous, committed, and flexible.
• Strong team spirit and excellent interpersonal skills.

OFFER

• A stimulating scientific position within a high-potential innovative biotech company.
• The opportunity to work in a science-driven, dynamic, human‐sized, respectful, and professional environment.
• A challenging scientific and business growth in which you get to bring your knowledge and skills.
• A permanent contract and an attractive salary package in line with the position responsibilities and your experience.

INTERESTED?

Please send your CV together with an adapted cover letter to https://www.pahrtners.be/fr/offres-demploi/research-assistant-immunology-in-vivo-biology-mf/ or via recruitment@pahrtners.be  

Your application and related information will remain strictly confidential.